Ulcerative colitis (UC) is a lifelong condition that causes inflammation and ulcers inside your colon (large intestine). UC is one of the most common types of inflammatory bowel disease (IBD), alongside Crohn’s disease. What Is Ulcerative Colitis? Ulcerative colitis (UC) is an inflammatory bowel disease. It causes irritation, inflammation, and ulcers in the lining of your large intestine (also called your colon). Ulcerative colitis (UC) is an inflammatory bowel disease affecting the colon and rectum, causing significant digestive distress. While there is no cure, treatments like medications and lifestyle changes can help manage the symptoms. Ulcerative colitis (UC) is the most common type of inflammatory bowel disease (IBD). It affects the inner lining of the colon and rectum, causing complete damage to the lining. People with UC often experience blood or mucous in their stool (poop) and feel an urgent need to empty their bowels. Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1][7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1] In this video, we'll cover the basics of ulcerative colitis. What is it? Who gets it? The symptoms, diagnosis, and treatment. Whether you're looking for answers for yourself or someone you love, we're here to give you the best information available. Crohn's disease vs. ulcerative colitis Crohn's disease vs. ulcerative colitis. translate Clinical Features Abdominal cramps and diarrhea (often bloody) Classification Mild 4 bowel movements per day No systemic symptoms Few extraintestinal manifestations Occasional constipation and rectal bleeding Moderate Colitis extends to splenic.